One solution to this problem is installing insect screens on your indoor and outdoor vents.
Floor vents and spiders.
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If you re seeing small insects and spiders in your house there s a good chance that they crawled in through a duct opening.
Some vents are vertical and it is difficult place a trap inside for these types what i sometimes do is place wide strips of clear packing tape over the vent leaving thin slits 1 4 to 1 2 inch wide so that the air can still come through but when the insect tries to crawl out to freedom he will get stuck and die.
Replace or fix torn window screens and caulk up gaps around.
Air vents are the number one way for bugs to get in.
Cover vents with fine mesh insect screens.
If there are particular areas that you have noticed spiders hanging out make sure that you spray them as well.
Feel free to spray spiders directly if they come across your path.
Many spiders prefer dark areas and will hide in cracks to retreat.
Apply caulk around wires cables faucets and electrical components that run to the outside.
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Spiders tend to prefer places like basements crawl spaces upper corners of rooms and attics as well as sub floor air vents.
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Spray the spider solution along all entryways to your home including doorways window sills around a fireplace baseboards and vents.
Take preventative measures outdoors to keep the spiders from coming in.